Because saponins are natural surfactants showing the unique properties of foaming and emulsifying agents, they can act as a stabilizer in our experiments for AgNPs synthesis. Foaming is a common and very visible effect that can occur when surfactants are present in water. According to our experiment, when Lysimachia foenum-graecum Hance extract (LHE) was dissolved in deionized water, it produces a little foam on the solution surface. Surprisingly, saponins found in LHE is the main ingredient which plays an important role in the stabilization of AgNPs in water. However, the chemical constituent found in LH is triterpenoid saponins, flavonoids and glycosides. Commonly, it has been used to make perfume, pest repellent, alleviate pain and Chinese medical treatment for common colds and headaches. It is about 50 cm tall and has a scented smell, and is mostly found in the Guangxi and Yunnan provinces of China. LH is a plant in Lysimachia genus of the Primulaceae family ( Figure 1). Furthermore, antibacterial property has been studied to observe the antibacterial activity of these stabilized AgNPs. However, in this research we aimed to study the synthesis of AgNPs using a new kind of Chinese herbal plant extract called Lysimachia foenum-graecum Hance (LH) as a reducing and stabilizing agent to observe the stability of synthesized AgNPs. kessleri on the biosynthesis of AgNPs which showed a long-term stability at the higher pH values and indicated similar inhibitory antimicrobial activity as gelatin/sodium citrate-AgNPs against biofilm formation.
![is the size malvern zetasizer radius or diameter is the size malvern zetasizer radius or diameter](https://img.medicalexpo.com/images_me/photo-g/94317-12689972.jpg)
It was found that the biosynthesized silver nanoparticles showed a broad spectrum of antimicrobial activity and were most active against Staphylococcus aureus ( S. and co-workers used lingonberry and cranberry juices in a biosynthesis of silver nanoparticles and studied their antimicrobial activity. The synthesized AgNPs exhibited higher activity than AgNO 3 solution and leaves extract. leaves and investigated their synergistic effects with antibiotics. and co-workers synthesized silver nanoparticles using Urtica dioica Linn. and coworkers used the extract of Rosmarinus officinalis leaf and investigated its antimicrobial properties showing effective antibacterial and antifungal activities. and co-workers used the dried leaves extract of Pongamia pinnata (L) pierre for an extracellular synthesis of AgNPs. carota extract for the synthesis of AgNPs. and co-workers also used the extract of D. The results suggested that synthesised AgNPs had the highest antibacterial activity against Escherichia coli ( E. and co-workers used the Pedalium murex leaf extract for the synthesis of AgNPs and antibacterial activity has been studied. There have been many research articles focusing on the use of many kinds of plant extracts as a reducing agent for synthesis of nanoparticles especially silver nanoparticles (AgNPs). Nowadays, nanotechnology involving green synthesis of nanoparticles has become an eye-catching idea and has gained much importance and significance in recent years due to its great facility, clean processing, non-toxic chemicals used, cost-effectiveness, and being environmentally and ecofriendly. That is the reason why nanotechnology has received much attention from many researchers and scientists worldwide and has become more popular in both academic research and industry. The control of atoms or molecules in the structure of materials at the nanometer scale allows us to adjust the properties of materials for more specific applications. Nanotechnology is the integration of science and technology involving the fabrication or synthesis, design and analysis of materials at the nanometer scale. aureus showing an inhibition zone diameter of 19.08 ± 0.67 mm which is superior to Chloramphenicol. AgNPs with LHE 0.003 wt% affords the highest antibacterial effect to S.
![is the size malvern zetasizer radius or diameter is the size malvern zetasizer radius or diameter](https://ars.els-cdn.com/content/image/1-s2.0-S0168365919301130-gr3.jpg)
Furthermore, the obtained AgNPs colloidal solutions show superior antibacterial effect to gram-positive bacteria ( Staphylococcus aureus) comparing to Chloramphenicol (positive control). This can be confirmed by zeta potential measurements which afforded values approximately of 0 mV, indicating the steric stability of AgNPs colloidal solutions synthesized by LHE. Aqueous colloidal solutions of AgNPs reduced and stabilized by LHE show long-term stability due to the steric stabilization effect. The concentration of LHE used in this study was in the range of 0.003 to 1.0 wt%. In this study, the herbal plant of Lysimachia foenumgraecum Hance (LH) was extracted with deionized water and we are the first to successfully use LHE as reducing and stabilizing agents for the green synthesis of AgNPs. The Lysimachia foenumgraecum Hance extract (LHE) was used for silver nanoparticles (AgNPs) synthesis.